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  • Diazoxide is given by mouth and is used off label to treat low blood sugar associated with insulin-producing tumors of the pancreas. Give as directed by your veterinarian. Common side effects include drooling, lack of appetite, vomiting, and diarrhea. Do not use in pets that are allergic to it or thiazide diuretics, or in pets with low blood sugar due to anything other than a tumor. If a negative reaction occurs, please call your veterinary office.

  • Diclofenac ophthalmic is a topical nonsteroidal anti-inflammatory medication used to treat inflammatory eye conditions in cats, dogs, rabbits, avian species, and other animals. Diclofenac ophthalmic comes in liquid drop form.

  • Diethylstilbestrol is given by mouth and is used off label to treat urinary incontinence. Give as directed by your veterinarian. Side effects are uncommon when using a low dose, but may include mild vaginal spotting. It should not be used in pets that are allergic to it, in females with estrogen-sensitive tumors, in pets with anemia or low white blood cell counts, or in food production animals. If a negative reaction occurs, please call your veterinary office.

  • Digestive lubricants and hairball gels (e.g., Laxatone®) are oil-based lubricants that are given as supplements to help prevent and eliminate hairballs in cats. They come in oral gel format and are available in several flavors.

  • Digoxin is used off label and is given by mouth or injection to treat certain abnormal heart rhythms and certain types of congestive heart failure. Common side effects include vomiting, diarrhea, lack of appetite, weight loss, tiredness, or behavior changes.

  • Dilated cardiomyopathy (DCM) is a serious and often fatal condition in medium to larger breed dogs. Signs may be sudden or progressive in onset. Some signs include rapid breathing, increased effort with breathing, restless sleeping, coughing, or gagging, among others. Early and proper diagnosis is key, followed by treatment to give the best quality of life.

  • Diltiazem is given by mouth as a tablet, capsule, or compounded liquid, and is used off label to treat abnormal heart rhythms, high blood pressure, and other heart conditions. Common side effects include a slow heart rate in dogs and vomiting in cats. This medication should not be used in pets with hypersensitivity, severely low blood pressure, lung congestion, or certain abnormal heart rhythms.

  • Dimenhydrinate is given by mouth or injection and is used off label to treat nausea and motion sickness, and occasionally itchiness. Give as directed by your veterinarian. Common side effects include sleepiness, dry mouth, and difficulty urinating. Do not use in pets that are allergic to it or similar antihistamines, that are very young, or that are undergoing antigen skin testing within the next two weeks. If a negative reaction occurs, please call your veterinary office.

  • Dimethylglycine is given by mouth and is used off label and over the counter to enhance racing performance, as well as supplement the treatment for some cancers, diabetes, immune diseases, or cardiovascular diseases. Give as directed by your veterinarian. Side effects are uncommon and unreported. DMG should be used cautiously in pets that are pregnant, nursing, or debilitated. If a negative reaction occurs, please call your veterinary office.

  • Dinotefuran/permethrin/pyriproxyfen (brand name Vectra 3D®) is a topical (spot-on) antiparasitic drug that is applied directly to the skin. It is used to repel and kill fleas, ticks, mosquitoes, biting flies, sand flies, and biting/chewing lice in dogs and puppies that are at least 8 weeks of age and weigh at least 2.3 kg (5 lb). NEVER use in cats and avoid using in households with cats, if possible. Permethrin is poisonous to cats and any exposure may be fatal.